This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Tocris Bioscience
product type :
chemical
product name :
BAY 293
catalog :
6857/5
quantity :
5 mg
price :
287 USD
product information
brand :
Tocris, a Bio-Techne Brand
catalog number base :
6857
SKU :
6857/5
product name :
BAY 293
Description :
Potent KRas/SOS1 interaction inhibitor
target :
Ras GTPase Inhibitors
category :
Small Molecules
unit size :
5 mg
purity :
98%
observed molecular weight :
448.59
url print :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
BAY 293 is a potent KRas/son of sevenless 1 (SOS1) interaction inhibitor (IC50 = 21 nM); active R -enantiomer. Downregulates active RAS in tumor cells. Inhibits RAS-RAF-MEK-ERK pathway. Exhibits synergistic effects with KRASG12C inhibitor ARS-853. . Negative control also available.
extended description :
Potent KRas/SOS1 interaction inhibitor
chemical name text :
(R)-6,7-Dimethoxy-2-methyl-N-[1-[4-[2-[(methylamino)methyl]phenyl]thiophene-2-yl]ethyl]quinazolin-4-amine
formula :
C 25 H 28 N 4 O 2 S
formula text :
C25H28N4O2S
cas num :
2244904-70-7
USD :
287 USD
product details :
Potent KRas/SOS1 interaction inhibitor
storage :
Store at -20°C
company information

Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com800-343-7475
headquarters: UK
questions and comments