chemical

alpha-Mangostin

6856

10 mg (also 50 mg)

99 USD

6856

6856/10

alpha-Mangostin

Inhibits proliferation and induces apoptosis selectively in pancreatic CSCs and cancer cell lines

Cancer Stem Cells

Small Molecules

10 mg (also 50 mg)

98%

410.47

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Xanthone derivative. Inhibits proliferation and induces apoptosis selectively in pancreatic CSCs and cancer cell lines. Also suppresses the invasive and metastatic ability of pancreatic CSCs by modulation of cadherin expression and suppressing the transcription factors Snail and Slug. Attenuates the expression of Nanog and pluripotency promoting transcription factors, and inhibits Nanog binding. Downregulates the PI 3-K/Akt pathway. Inhibits self-renewal of CSCs isolated from human primary tumors and KrasG12D mice. Inhibits MRSA and VRE. Antibacterial, antifungal, antimalarial, anticarcinogenic, antiatherogenic, anti-inflammatory, antioxidant and neuroprotective.

6856

alpha-Mangostin a-Mangostin Inhibits proliferation induces apoptosis pancreatic CSCs anticarcinogenic cadherin expression modulator Nanog pluripotency promoting factors MRSA VRE neuroprotective PI3K Akt pathway antimalarial antioxidant neuroprotective can Cancer Stem Cells Cell Adhesion Molecules Antibiotics PI 3-Kinase Antimalarials Antioxidants 6856,

Inhibits proliferation and induces apoptosis selectively in pancreatic CSCs and cancer cell lines

1,3,6-Trihydroxy-7-methoxy-2,8-bis(3-methyl-2-buten-1-yl)-9H-xanthen-9-one

C 24 H 26 O 6

C24H26O6

11/1/47

99

99 USD

Store at -20°C