This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Tocris Bioscience
product type :
chemical
product name :
alpha-Mangostin
catalog :
6856/10
quantity :
10 mg (also 50 mg)
price :
126 USD
product information
brand :
Tocris, a Bio-Techne brand
catalog number base :
6856
SKU :
6856/10
product name :
alpha-Mangostin
description :
Inhibits proliferation and induces apoptosis selectively in pancreatic CSCs and cancer cell lines
target :
Cancer Stem Cells
unit size :
10 mg (also 50 mg)
category :
Small Molecules
purity :
98%
storage :
Store at -20°C
observed molecular weight :
410.47
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
-Mangostin is a xanthone derivative. Inhibits proliferation and induces apoptosis selectively in pancreatic CSCs and cancer cell lines. Also suppresses the invasive and metastatic ability of pancreatic CSCs by modulation of cadherin expression and suppressing the transcription factors Snail and Slug. Attenuates the expression of Nanog and pluripotency promoting transcription factors, and inhibits Nanog binding. Downregulates the PI 3-K/Akt pathway. Inhibits self-renewal of CSCs isolated from human primary tumors and KrasG12D mice. Inhibits MRSA and VRE. Antibacterial, antifungal, antimalarial, anticarcinogenic, antiatherogenic, anti-inflammatory, antioxidant and neuroprotective.
product keywords :
alpha-Mangostin a-Mangostin Inhibits proliferation induces apoptosis pancreatic CSCs anticarcinogenic cadherin expression modulator Nanog pluripotency promoting factors MRSA VRE neuroprotective PI3K Akt pathway antimalarial antioxidant neuroprotective can Cancer Stem Cells Cell Adhesion Molecules Antibiotics PI 3-Kinase Antimalarials Antioxidants 6856,
extended description :
Inhibits proliferation and induces apoptosis selectively in pancreatic CSCs and cancer cell lines
chemical name text :
1,3,6-Trihydroxy-7-methoxy-2,8-bis(3-methyl-2-buten-1-yl)-9H-xanthen-9-one
formula :
C24H26O6
formula text :
C24H26O6
cas num :
11/1/47
USD :
124
USD 2025 :
126 USD
product details :
Inhibits proliferation and induces apoptosis selectively in pancreatic CSCs and cancer cell lines
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK