LY 3009120 | Tocris Bioscience 6854 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

LY 3009120

catalog :

6854

quantity :

10 mg (also 50 mg)

price :

101 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

6854

SKU :

6854/10

product name :

LY 3009120

description :

Potent pan-Raf kinase inhibitor

target :

Raf Kinase Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

424.52

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent pan-Raf kinase inhibitor (IC50 values are 31 - 47, 42 and 44 nM for b-RAF, c-RAF and a-RAF in A375 cells, respectively). Also inhibits kinase activity of Raf hetero- and homodimers. Displays antiproliferative effects against b-RAF and Ras mutant melanoma cells. Inhibits MEK and ERK phosphorylation, and b-RAF and Ras mutant tumor growth in mouse xenograft models.

catalog number base :

6854

product keywords :

LY3009120 potent pan raf inhibitors inhibition bRAf cRAF aRAF inhibits Raf Kinase 6854,

extended description :

Potent pan-Raf kinase inhibitor

chemical name text :

N-(3,3-Dimethylbutyl)-N -[2-fluoro-4-methyl-5-[7-methyl-2-(methylamino)pyrido[2,3-d]pyrimidin-6-yl]phenyl]urea

formula :

C 23 H 29 FN 6 O

formula text :

C23H29FN6O

cas num :

1454682-72-4

2020 USD :

2021 USD :

101 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage