product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
RCM 1
catalog :
6845
quantity :
10 mg (also 50 mg)
price :
155 USD
more info or order :
product information
brand :
Tocris
master code :
6845
SKU :
6845/10
product name :
RCM 1
description :
FOXM1 inhibitor
target :
FoxM1
category :
Small Molecules
unit size :
10 mg (also 50 mg)
main entrez gene id :
2305
purity :
98%
observed molecular weight :
424.58
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Forkhead box M1 (FOXM1) transcription factor inhibitor (IC50 = 0.72 M). Inhibits expression of FOXM1 target genes. Induces FOXM1 protein degradation in vitro . Reduces airway resistance, increases lung compliance and decreases proinflammatory cytokine production in allergen-exposed mice.
catalog number base :
6845
product keywords :
RCM1 forkhead box m1 FOXM1 transcription factor inhibitors inhibits allergy cytokine production goblet cells anti-inflammatory anti-asthma Other Transcription Factors 6845, FoxM 1, FOX M1
extended description :
FOXM1 inhibitor
chemical name text :
2-[[2-Oxo-2-(2-thienyl)ethyl]thio]-4,6-di-2-thienyl-3-pyridinecarbonitrile
formula :
C 20 H 12 N 2 OS 4
formula text :
C20H12N2OS4
cas num :
339163-65-4
2020 USD :
149
2021 USD :
155 USD
alt names :
FKHL16, FKHL16trident, forkhead box M1, forkhead box protein M1, Forkhead, drosophila, homolog-like 16, forkhead-like 16, Forkhead-related protein FKHL16, Hepatocyte nuclear factor 3 forkhead homolog 11, HFH-11, HFH11FOXM1B, HFH-11M-phase phosphoprotein 2, HNF-3, HNF-3/fork-head homolog 11, INS-1, MPHOSPH2, MPP-2, MPP2MPM-2 reactive phosphoprotein 2, PIG29, TGT3, Transcription factor Trident, Trident, WIN, Winged-helix factor from INS-1 cells
storage :
Store at -20°C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK