GSK 923295A | Tocris Bioscience 6837 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

GSK 923295A

catalog :

6837

quantity :

25 mg

price :

565 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

6837

SKU :

6837/25

product name :

GSK 923295A

description :

Potent and selective centromere associated protein E (CENP-E) allosteric inhibitor

target :

Kinesin Inhibitors

category :

Small Molecules

unit size :

25 mg

purity :

97%

observed molecular weight :

592.13

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent and selective centromere associated protein E (CENP-E) allosteric inhibitor (IC50 = 22 nM); does not compete with ATP. Exhibits selectivity over a panel of other kinesins ( 25% inhibition at 50 M). Inhibits tumor cell growth in vitro . Induces mitotic arrest and regression of human tumor xenografts in vivo .

catalog number base :

6837

product keywords :

GSK923295A ATPase Potent selective centromere associated protein E CENP-E allosteric inhibitors inhibits mitotic kinesin mitosis Kinesin 6837,

extended description :

Potent and selective centromere associated protein E (CENP-E) allosteric inhibitor

chemical name text :

3-Chloro-N-[(1S)-2-[[2-(dimethylamino)acetyl]amino]-1-[[4-[8-[(1S)-1-hydroxyethyl]imidazo[1,2-a]pyridin-2-yl]phenyl]methyl]ethyl]-4-(1-methylethoxy)benzamide

formula :

C 32 H 38 ClN 5 O 4

formula text :

C32H38ClN5O4

cas num :

1088965-37-0

2020 USD :

565

2021 USD :

565 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage