ZAP 180013 | Tocris Bioscience 6821/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

ZAP 180013

catalog :

6821/10

quantity :

10 mg (also 50 mg)

price :

132 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

MasterCode :

6821

SKU :

6821/10

product name :

ZAP 180013

target :

Additional RTK Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

454.32

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

ZAP 180013 is a zeta-chain-associated protein kinase 70 (Zap70) inhibitor (IC50 = 1.8 M in fluorescence polarization assay). Inhibits the interaction of Zap70 SH2 domain with immunoreceptor tyrosine-based activation motif (ITAMs), within the T-cell antigen receptor (TCR) signaling pathway.

extended description :

Zap70 inhibitor; inhibits interaction with ITAMs

chemical name text :

5-Chloro-N-[(4-chlorophenyl)methyl]-2-(ethylsulfonyl)-N-(2-furanylmethyl)-4-pyrimidinecarboxamide

formula :

C 19 H 17 Cl 2 N 3 O 4 S

formula text :

C19H17Cl2N3O4S

cas num :

873080-25-2

USD :

132 USD

product details :

Zap70 inhibitor; inhibits interaction with ITAMs

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage