Mefloquine hydrochloride | Tocris Bioscience 6819/50 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Mefloquine hydrochloride

catalog :

6819/50

quantity :

50 mg

price :

59 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

MasterCode :

6819

SKU :

6819/50

product name :

Mefloquine hydrochloride

target :

Gap Channel Blockers

category :

Small Molecules

unit size :

50 mg

purity :

98%

observed molecular weight :

414.77

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Mefloquine hydrochloride is a Cx36 and Cx50 gap channel blocker (IC50 values are 0.3 and 1.1 M, resepctively). Blocks gap junctional-coupling between interneurons in neocortical slices. Also antimalarial. Bind 80S ribosome of Plasmodium falciparum to inhibit protein synthesis. Improves survival in P berghei -infected mice. Additionally exhibits antischistosomal activity in vitro and in vivo . Exhibits antiviral activities against SARS-CoV-2 (IC50 10 M).

extended description :

Cx36 and Cx50 gap channel blocker; also antimalarial and antischistosomal

chemical name text :

( S)-rel- -(2R)-2-Piperidinyl-2,3-bis(trifluoromethyl-4-quinolinemethanol hydrochloride

formula :

C 17 H 16 F 6 N 2O.HCl

formula text :

C17H16F6N2O.HCl

cas num :

51773-92-3

USD :

59 USD

product details :

Cx36 and Cx50 gap channel blocker; also antimalarial and antischistosomal

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage