BAY 8002 | Tocris Bioscience 6817 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

BAY 8002

catalog :

6817

quantity :

10 mg (also 50 mg)

price :

129 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

6817

SKU :

6817/10

product name :

BAY 8002

description :

Potent dual MCT1/2 inhibitor; orally bioavailable

target :

Monocarboxylate Transporter Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

415.85

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent dual MCT1/2 inhibitor (IC50 values are 3, 8, and 12 nM at rat (C6), human (DLD-1) and mouse (4T1) MCT1 respectively; IC50 values of human MCT1, MCT2, and MCT4 isoforms recombinantly expressed in X. laevis oocytes are 1, 5 and 500 nM, respectively); suppresses bidirectional lactate transport. Inhibits cellular SNARF-5 fluorescence change (IC50 = 85 nM) in MCT1-expressing DLD-1 cells. Arrests growth and increases intratumor lactate levels of Raji tumor xenografts in mice. Orally bioavailable.

catalog number base :

6817

product keywords :

BAY8002 potent dual MCT1/2 inhibitors inhibits MCT1 MCT2 orally bioavailable lactate Monocarboxylate Transporters 6817,

extended description :

Potent dual MCT1/2 inhibitor; orally bioavailable

chemical name text :

2-[[2-Chloro-5-(phenylsulfonyl)benzoyl]amino]benzoic acid

formula :

C 20 H 14 ClNO 5 S

formula text :

C20H14ClNO5S

cas num :

724440-27-1

2020 USD :

125

2021 USD :

129 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage