GeA-69 | Tocris Bioscience 6795/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

GeA-69

catalog :

6795/10

quantity :

10 mg (also 50 mg)

price :

137 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 6795 - GeA-69 C20H16N2O CAS No. 2143475-98-1

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

6795

SKU :

6795/10

product name :

GeA-69

description :

Selective allosteric PARP14 inhibitor

target :

PARP

unit size :

10 mg (also 50 mg)

category :

Small Molecules

purity :

98%

storage :

Store at -20°C

observed molecular weight :

300.35

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

GeA-69 is a selective allosteric inhibitor of poly (ADP-ribose) polymerase 14 (PARP14) macrodomain 2 (MD2) (IC50 = 720 nM, Kd = 860 nM). It inhibits adenosine diphosphate ribose (ADPR) binding to the macrodomain 2 of PARP14 and prevents PARP14 MD2 localization to DNA damage sites in intact cells. GeA-69 is highly cell permeable.

product keywords :

GeA69 GeA 69 PARP inhibitors inhibits PolyADP ribose Polymerases Poly(ADP ribose) Polymerase adenosine diphosphate ribose ADPR selective MD2 macrodomain 2 Poly(ADP-ribose) Polymerase 6795,

extended description :

Selective allosteric PARP14 inhibitor

chemical name text :

N-[2-(9H-Carbazol-1-yl)phenyl]acetamide

formula :

C20H16N2O

formula text :

C20H16N2O

cas num :

2143475-98-1

USD :

152

USD 2025 :

137 USD

product details :

Selective allosteric PARP14 inhibitor

alt names :

ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase), ADPRT, ADPRT 1, ADPRTADP-ribosyltransferase NAD(+), ARTD8, BAL2, EC 2.4.2, EC 2.4.2.30, KIAA1268, NAD(+) ADP-ribosyltransferase 1, PARP apoptosis, PARP1, PARP-1, PARP-14, PARPADPRT1, poly (ADP-ribose) polymerase 1, poly (ADP-ribose) polymerase family, member 1, poly [ADP-ribose] polymerase 1, poly(ADP-ribose) polymerase, poly(ADP-ribose) synthetase, poly(ADP-ribosyl)transferase, Poly[ADP-ribose] synthase 1, PPOL, PPOLpADPRT-1

more info or order :

Tocris Bioscience product webpage