BC-LI-0186 | Tocris Bioscience 6791/5 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

BC-LI-0186

catalog :

6791/5

quantity :

5 mg (also 25 mg)

price :

108 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 6791 - BC-LI-0186 C22H27N3O4S CAS No. 695207-56-8

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

6791

SKU :

6791/5

product name :

BC-LI-0186

description :

Leucyl-tRNA synthase (TRS)/Ras-related GTP-binding protein D (RagD) interaction inhibitor

target :

Ras GTPase Inhibitors

unit size :

5 mg (also 25 mg)

category :

Small Molecules

purity :

98%

storage :

Store at -20°C

observed molecular weight :

429.54

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

BC-LI-0186 is a potent and high affinity leucyl-tRNA synthase (TRS)/Ras-related GTP-binding protein D (RagD) interaction inhibitor (IC50 = 46.1 nM; Kd = 42.1 nM for binding to LRS). Inhibits mTOR complex 1 activity by blocking binding to LRS without affecting catalytic activity. Inhibits leucine-induced translocation of LRS to the lysosome.

product keywords :

Leucyl-RNA synthase TRS RagD GTPase interaction inhibitor mTOR complex translocation lysosome Other Synthases/Synthetases Ras GTPases mTOR 6791, Ras, GTP ase

extended description :

Leucyl-tRNA synthase (TRS)/Ras-related GTP-binding protein D (RagD) interaction inhibitor

chemical name text :

4-[2,5-Dihydro-2,3-dimethyl-4-(1-methylethyl)-5-oxo-1H-pyrazol-1-yl]-N-(2-phenoxyethyl)benzenesulfonamide

formula :

C22H27N3O4S

formula text :

C22H27N3O4S

cas num :

695207-56-8

USD :

119

USD 2025 :

108 USD

product details :

Leucyl-tRNA synthase (TRS)/Ras-related GTP-binding protein D (RagD) interaction inhibitor

more info or order :

Tocris Bioscience product webpage