Quizartinib | Tocris Bioscience 6788/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Quizartinib

catalog :

6788/10

quantity :

10 mg (also 50 mg)

price :

189 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Hultmark S, Baudet A, Schmiderer L, Prabhala P, Palma Tortosa S, Sandén C, et al. Combinatorial molecule screening identified a novel diterpene and the BET inhibitor CPI-203 as differentiation inducers of primary acute myeloid leukemia cells. Haematologica. 2021;106:2566-2577 pubmed publisher

image

image 1 :

Cat.No. 6788 - Quizartinib C29H32N6O4S CAS No. 950769-58-1

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

6788

SKU :

6788/10

product name :

Quizartinib

description :

Highly potent FLT3 inhibitor

target :

Flt-3 Inhibitors

unit size :

10 mg (also 50 mg)

category :

Small Molecules

purity :

98%

storage :

Store at -20°C

observed molecular weight :

560.67

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Quizartinib is a highly potent FMS-like receptor tyrosine kinase-3 (FLT3) inhibitor (Kd = 1.6 nM, IC50 = 0.56 nM in MV4-11 cell proliferation assay). Displays 10-fold selectivity for FLT3 over panel of 400 kinases. Inhibits FLT3 activity and displays antitumor properties in a mouse MV4-11 tumor xenograft model.

product keywords :

FLT3 inhibitors inhibits FMS-like receptor tyrosine kinase-3 CD135 acute myeloid leukemia AML FLT3 6788,

extended description :

Highly potent FLT3 inhibitor

chemical name text :

N-[5-(1,1-Dimethylethyl)-3-isoxazolyl]-N -[4-[7-[2-(4-morpholinyl)ethoxy]imidazo[2,1-b]benzothiazol-2-yl]phenyl]urea

formula :

C29H32N6O4S

formula text :

C29H32N6O4S

cas num :

950769-58-1

USD :

187

USD 2025 :

189 USD

product details :

Highly potent FLT3 inhibitor

more info or order :

Tocris Bioscience product webpage