TAK 375 | Tocris Bioscience 6777 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

TAK 375

catalog :

6777

quantity :

10 mg (also 50 mg)

price :

101 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

6777

SKU :

6777/10

product name :

TAK 375

description :

Very high affinity and selective melatonin receptor agonist

target :

Melatonin (MT) Receptor Agonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

259.34

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Very high affinity and selective melatonin agonist (Ki values are 14 and 112 pM for human MT1 and MT2, respectively). Selective for human MT1 and MT2 over hamster MT3 and a range of other targets including benzodiazepine, opiate and dopamine receptors, ion channels and transporters. Accelerates return to normal circadian rhythm in rats after phase shift, without affecting learning and memory. Also reduces infarct size in rat heart in vitro post ischemia-reperfusion.

catalog number base :

6777

product keywords :

TAK375 melatonin receptor agonists agonism selective very high affinity MT1 MT2 circadian rhythm Ramelteon Melatonin (MT) Receptors 6777,

extended description :

Very high affinity and selective melatonin receptor agonist

chemical name text :

N-[2-[(8S)-1,6,7,8-Tetrahydro-2H-indeno[5,4-b]furan-8-yl]ethyl]propanamide

formula :

C 16 H 21 NO 2

formula text :

C16H21NO2

cas num :

196597-26-9

2020 USD :

2021 USD :

101 USD

alt names :

Ramelteon

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage