product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
TAK 375
catalog :
6777/10
quantity :
10 mg (also 50 mg)
price :
115 USD
more info or order :
citations: 1
image
image 1 :
Cat.No. 6777 - TAK 375 C16H21NO2 CAS No. 196597-26-9
product information
brand :
Tocris
catalog number base :
6777
SKU :
6777/10
product name :
TAK 375
units size :
10 mg (also 50 mg)
description :
Very high affinity and selective melatonin receptor agonist
target :
Melatonin (MT) Receptor Agonists
category :
Small Molecules
purity :
98%
observed molecular weight :
259.34
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
review stars :
4
details of functionality :
TAK 375 is a very high affinity and selective melatonin agonist (Ki values are 14 and 112 pM for human MT1 and MT2, respectively). Selective for human MT1 and MT2 over hamster MT3 and a range of other targets including benzodiazepine, opiate and dopamine receptors, ion channels and transporters. Accelerates return to normal circadian rhythm in rats after phase shift, without affecting learning and memory. Also reduces infarct size in rat heart in vitro post ischemia-reperfusion.
top caption :
Very high affinity and selective melatonin receptor agonist
extended description :
Very high affinity and selective melatonin receptor agonist
chemical name text :
N-[2-[(8S)-1,6,7,8-Tetrahydro-2H-indeno[5,4-b]furan-8-yl]ethyl]propanamide
formula :
C16H21NO2
formula text :
C16H21NO2
cas num :
196597-26-9
USD :
115 USD
product details :
Very high affinity and selective melatonin receptor agonist
alt names :
Ramelteon
storage :
Store at -20°C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com800-343-7475
headquarters: UK
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