product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
ST 045849
catalog :
6775
quantity :
10 mg (also 50 mg)
price :
205 USD
more info or order :
Tocris Bioscience product webpage
image
image 1 :
Tocris Bioscience 6775 image 1
Cat.No. 6775 - ST 045849 C23H27ClN2O3S CAS No. 442665-87-4
product information
brand :
Tocris
master code :
6775
SKU :
6775/10
product name :
ST 045849
description :
O-GlcNAc transferase (OGT) inhibitor
target :
Other Transferase Inhibitors
category :
Small Molecules
unit size :
10 mg (also 50 mg)
purity :
98%
observed molecular weight :
446.99
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
O-GlcNAc transferase (OGT) inhibitor (IC50 = 53 M). Reduces proliferation and viability of prostate cancer cells in vitro . Depletes intracellular alanine and decreases glucose consumption by cancer cells. Decreases markers of ER stress and apoptosis in pregnant diabetic mice and reduces neural tube defects in embryos from diabetic mice.
catalog number base :
6775
product keywords :
ST045849 O-GlcNAc O-linked N-acetylglucosamine transferase OGT inhibitors inhibits glycosylation glycolysis O-GlcNAcylation hyperglycemia Other Transferases 6775,
extended description :
O-GlcNAc transferase (OGT) inhibitor
chemical name text :
2-[(4-Chlorophenyl)imino]tetrahydro-4-oxo-3-(2-tricyclo[3.3.1.13,7]dec-1-ylethyl)-2H-1,3-thiazine-6-carboxylic acid
formula :
C 23 H 27 ClN 2 O 3 S
formula text :
C23H27ClN2O3S
cas num :
442665-87-4
2020 USD :
205
2021 USD :
205 USD
storage :
Store at -20°C
more info or order :
Tocris Bioscience product webpage
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK