ST 045849 | Tocris Bioscience 6775/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

ST 045849

catalog :

6775/10

quantity :

10 mg (also 50 mg)

price :

255 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Soria L, Makris G, D Alessio A, De Angelis A, Boffa I, Pravata V, et al. O-GlcNAcylation enhances CPS1 catalytic efficiency for ammonia and promotes ureagenesis. Nat Commun. 2022;13:5212 pubmed publisher

image

image 1 :

Cat.No. 6775 - ST 045849 C23H27ClN2O3S CAS No. 442665-87-4

product information

brand :

Tocris

MasterCode :

6775

SKU :

6775/10

product name :

ST 045849

target :

Other Transferase Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

446.99

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

ST 045849 is an O-GlcNAc transferase (OGT) inhibitor (IC50 = 53 M). Reduces proliferation and viability of prostate cancer cells in vitro . Depletes intracellular alanine and decreases glucose consumption by cancer cells. Decreases markers of ER stress and apoptosis in pregnant diabetic mice and reduces neural tube defects in embryos from diabetic mice.

extended description :

O-GlcNAc transferase (OGT) inhibitor

chemical name text :

2-[(4-Chlorophenyl)imino]tetrahydro-4-oxo-3-(2-tricyclo[3.3.1.13,7]dec-1-ylethyl)-2H-1,3-thiazine-6-carboxylic acid

formula :

C 23 H 27 ClN 2 O 3 S

formula text :

C23H27ClN2O3S

cas num :

442665-87-4

USD :

255 USD

product details :

O-GlcNAc transferase (OGT) inhibitor

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage