This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Tocris Bioscience
product type :
chemical
product name :
PHPS1 sodium salt
catalog :
6771/5
quantity :
5 mg (also 25 mg)
price :
179 USD
citations: 1
Reference
Stan x10d in P, Song M, Alajbeg I, Mitre x10d i x107 D. Human Oral Mucosa Stem Cells Increase Survival of Neurons Affected by In Vitro Anoxia and Improve Recovery of Mice Affected by Stroke Through Time-limited Secretion of miR-514A-3p. Cell Mol Neurobiol. 2023;43:1975-1988 pubmed publisher
product information
brand :
Tocris, a Bio-Techne brand
catalog number base :
6771
SKU :
6771/5
product name :
PHPS1 sodium salt
description :
Shp2 (PTPN11) inhibitor
target :
Protein Tyrosine Phosphatase Inhibitors
unit size :
5 mg (also 25 mg)
category :
Small Molecules
purity :
98%
storage :
Store at -20°C
observed molecular weight :
487.42
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
PHPS1 sodium salt is a Shp2 (PTPN11) inhibitor (IC50 = 2.1 M). Inhibits hepatocyte growth factor-stimulated epithelial cell scattering and branching morphogenesis in vitro . Increases myelin basic protein (MBP) levels in zebrafish embryo spinal cord. Also ameliorates bleomycin-induced pulmonary and dermal fibrosis in vivo .
product keywords :
shp2 ptpn11 inhibitors inhibits myelination fibrosis Protein Tyrosine Phosphatases 6771,
extended description :
Shp2 (PTPN11) inhibitor
chemical name text :
4-[2-[1,5-Dihydro-3-(4-nitrophenyl)-5-oxo-1-phenyl-4H-pyrazol-4-ylidene]hydrazinyl]benzenesulfonic acid sodium salt
formula :
C21H14N5O6SNa
formula text :
C21H14N5O6SNa
USD :
198
USD 2025 :
179 USD
product details :
Shp2 (PTPN11) inhibitor
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK