ABT 639 | Tocris Bioscience 6770 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

ABT 639

catalog :

6770

quantity :

10 mg

price :

220 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

6770

SKU :

6770/10

product name :

ABT 639

description :

CaV3.2 and CaV3.1 channel blocker; orally bioavailable

target :

Cav3.x Channel Blockers

category :

Small Molecules

unit size :

10 mg

purity :

98%

observed molecular weight :

455.91

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

CaV3.2 channel blocker (IC50 = 2.3 M). Also blocks low voltage-activated (CaV3.1) currents in native rat DRG neurons (IC50 = 7.6 M). Exhibits little or no activity at other ion channels and receptors. Displays antinociceptive effects in a mechanical hyperalgesia model in vivo . Orally bioavailable.

catalog number base :

6770

product keywords :

ABT639 T-type calcium channel blockers blocks CaV3.2 CaV3.1 antinociceptive orally bioavailable Cav3.x Channels 6770, Voltage-gated calcium channel blocker, voltage gated calcium channel, high-voltage activated Ca2+ channel, high voltage gated ca2+ channel

extended description :

CaV3.2 and CaV3.1 channel blocker; orally bioavailable

chemical name text :

4-Chloro-2-fluoro-N-(2-fluorophenyl)-5-[[(8aR)-hexahydropyrrolo[1,2-a]pyrazin-2(1H)-yl]carbonyl]benzenesulfonamide

formula :

C 20 H 20 ClF 2 N 3 O 3 S

formula text :

C20H20ClF2N3O3S

cas num :

1235560-28-7

2020 USD :

215

2021 USD :

220 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage