AC 1903 | Tocris Bioscience 6766/5 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

AC 1903

catalog :

6766/5

quantity :

5 mg (also 25 mg)

price :

83 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 6766 - AC 1903 C19H17N3O CAS No. 831234-13-0

product information

brand :

Tocris

master code :

6766

SKU :

6766/5

rank :

0.06

product name :

AC 1903

description :

Selective TRPC5 inhibitor

target :

TRPC Channel Blockers

category :

Small Molecules

sizes available :

5 mg (also 25 mg)

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

AC 1903 is a selective TRPC5 blocker (IC50 = 13.6 M). Also displays weak inhibition at TRPC4 (IC50 >100 M) but not TRPC6. Exhibits no effect against a standard panel of profiling kinases. Blocks TRPC5 channel activity in glomeruli of proteinuric rats. Suppresses severe proteinuria and prevents podocyte loss in a transgenic rat model of focal segmental glomerulosclerosis (FSGS).

extended description :

Selective TRPC5 inhibitor

chemical name text :

N-(2-Furanylmethyl)-1-(phenylmethyl)-1H-benzimidazol-2-amine

formula :

C 19 H 17 N 3 O

formula text :

C19H17N3O

cas num :

831234-13-0

USD :

83 USD

product details :

Selective TRPC5 inhibitor

storage :

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

more info or order :

Tocris Bioscience product webpage