B 973B | Tocris Bioscience 6764 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

B 973B

catalog :

6764

quantity :

10 mg (also 50 mg)

price :

245 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

6764

SKU :

6764/10

product name :

B 973B

description :

Positive allosteric modulator of 7 nAChRs; analgesic

target :

Nicotinic (a7) Receptor Modulators

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

452.5

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Positive allosteric modulator of 7 nAChRs (EC50 ~0.3 active enantiomer. Increases potency of acetylcholine (EC50 values are 0.007 mM and 0.3 mM in the presence and absence of B 937B, respectively). Potentiates peak acetylcholine-induced currents 6-fold relative to maximal acetylcholine, and slows channel desensitization, resulting in a 6900-fold increase in charge transfer. Decreases paw edema in vivo . Analgesic.

catalog number base :

6764

product keywords :

B973B B973 Positive allosteric modulators of 7 nAChRs acetylcholine nicotinic receptors PAMs (-)-( S )-B 973B (-)-(S)-B 973B Nicotinic (a7) Receptors 6764,

extended description :

Positive allosteric modulator of 7 nAChRs; analgesic

chemical name text :

3,4-Difluoro-N-[(1S)-1-[6-[4-(2-pyridinyl)-1-piperazinyl]-2-pyrazinyl]ethyl]benzenepropanamide

formula :

C 24 H 26 F 2 N 6 O

formula text :

C24H26F2N6O

cas num :

2244989-34-0

2020 USD :

245

2021 USD :

245 USD

alt names :

(-)-( S )-B 973B

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage