AVE 1625 | Tocris Bioscience 6763 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

AVE 1625

catalog :

6763

quantity :

10 mg (also 50 mg)

price :

243 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

6763

SKU :

6763/10

product name :

AVE 1625

description :

Potent and selective CB1 receptor antagonist

target :

Cannabinoid R1/CB1 Antagonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

497.38

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent and selective CB1 receptor antagonist (IC50 values are 25 and 10 nM for human and rat CB1R, respectively). Exhibits 400-fold selectivity for CB1 over CB2 receptors. Attenuates Olanzapine (Cat. No. 4349) induced weight gain and food intake in rats with no effect on energy expenditure or motility. Also improves cognitive function in rodent schizophrenia models and ameliorates extrapyramidal side-effects of antipsychotics.

catalog number base :

6763

product keywords :

AVE1625 cannabinoid receptor antagonist potent selective CB1 CB1R anti-obesity Drinabant CB1 Receptors 6763,

extended description :

Potent and selective CB1 receptor antagonist

chemical name text :

N-[1-[Bis(4-chlorophenyl)methyl]-3-azetidinyl]-N-(3,5-difluorophenyl)methanesulfonamide

formula :

C 23 H 20 Cl 2 F 2 N 2 O 2 S

formula text :

C23H20Cl2F2N2O2S

cas num :

358970-97-5

2020 USD :

235

2021 USD :

243 USD

alt names :

Drinabant

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage