CLP 290 | Tocris Bioscience 6758 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

CLP 290

catalog :

6758

quantity :

10 mg (also 50 mg)

price :

210 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 6758 - CLP 290 C19H21FN4O3S CAS No. 1181083-81-7

product information

brand :

Tocris

master code :

6758

SKU :

6758/10

product name :

CLP 290

description :

K+/Cl- cotransporter 2 (KCC2) activator; orally bioavailable prodrug of CLP 257 (Cat. No.5242)

target :

KCC2 Activators

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

404.46

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

K+/Cl- Cotransporter 2 (KCC2) activator. Activates spinal inhibitory interneurons, restores physiological neuronal activity in the spinal cord and induces functional recovery in a mouse model of spinal cord injury. Also decreases blood vasopressin and glucose levels in mice with Streptozotocin (Cat. No. 1621) induced diabetes mellitus. Orally bioavailable prodrug of CLP 257 (Cat. No.5242).

catalog number base :

6758

product keywords :

CLP290 CLP257 Selective KCC2 K+/Cl- cotransporters activators activates neuropathic pain orally bioavailable K+/Cl- Cotransporter 2 6758, SLC 12A5, SLC12 A5, KCC 2, Solute Carrier Family 12 (Potassium/Chloride Transporters) Member 3, Potassium-chloride cotransporter, Neuronal K-Cl cotransporter, K-Cl symporter, Electroneutral potassium-chloride cotransporter 22

extended description :

K+/Cl- cotransporter 2 (KCC2) activator; orally bioavailable prodrug of CLP 257 (Cat. No.5242)

chemical name text :

(Z)-5-Fluoro-2-((4-oxo-2-(tetrahydropyridazin-1(2H)-yl)thiazol-5(4H)-ylidene)methyl)phenyl pyrrolidine-1-carboxylate

formula :

C 19 H 21 FN 4 O 3 S

formula text :

C19H21FN4O3S

cas num :

1181083-81-7

2020 USD :

203

2021 USD :

210 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage