CLP 290 | Tocris Bioscience 6758/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

CLP 290

catalog :

6758/10

quantity :

10 mg (also 50 mg)

price :

265 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 6758 - CLP 290 C19H21FN4O3S CAS No. 1181083-81-7

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

6758

SKU :

6758/10

product name :

CLP 290

description :

K+/Cl- cotransporter 2 (KCC2) activator; orally bioavailable prodrug of CLP 257 (Cat. No.5242)

target :

KCC2 Activators

unit size :

10 mg (also 50 mg)

category :

Small Molecules

purity :

98%

storage :

Store at -20°C

observed molecular weight :

404.46

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

CLP 290 is a K+/Cl- Cotransporter 2 (KCC2) activator. Activates spinal inhibitory interneurons, restores physiological neuronal activity in the spinal cord and induces functional recovery in a mouse model of spinal cord injury. Also decreases blood vasopressin and glucose levels in mice with Streptozotocin (Cat. No. 1621) induced diabetes mellitus. Orally bioavailable prodrug of CLP 257 (Cat. No.5242).

product keywords :

CLP290 CLP257 Selective KCC2 K+/Cl- cotransporters activators activates neuropathic pain orally bioavailable K+/Cl- Cotransporter 2 6758, SLC 12A5, SLC12 A5, KCC 2, Solute Carrier Family 12 (Potassium/Chloride Transporters) Member 3, Potassium-chloride cotransporter, Neuronal K-Cl cotransporter, K-Cl symporter, Electroneutral potassium-chloride cotransporter 22

extended description :

K+/Cl- cotransporter 2 (KCC2) activator; orally bioavailable prodrug of CLP 257 (Cat. No.5242)

chemical name text :

(Z)-5-Fluoro-2-((4-oxo-2-(tetrahydropyridazin-1(2H)-yl)thiazol-5(4H)-ylidene)methyl)phenyl pyrrolidine-1-carboxylate

formula :

C19H21FN4O3S

formula text :

C19H21FN4O3S

cas num :

1181083-81-7

USD :

262

USD 2025 :

265 USD

product details :

K+/Cl- cotransporter 2 (KCC2) activator; orally bioavailable prodrug of CLP 257 (Cat. No.5242)

more info or order :

Tocris Bioscience product webpage