product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
CLP 290
catalog :
6758/10
quantity :
10 mg (also 50 mg)
price :
265 USD
more info or order :
image
image 1 :
Tocris Bioscience 6758/10 image 1
Cat.No. 6758 - CLP 290 C19H21FN4O3S CAS No. 1181083-81-7
product information
brand :
Tocris
catalog number base :
6758
SKU :
6758/10
product name :
CLP 290
units size :
10 mg (also 50 mg)
description :
K+/Cl- cotransporter 2 (KCC2) activator; orally bioavailable prodrug of CLP 257 (Cat. No.5242)
target :
KCC2 Activators
category :
Small Molecules
purity :
98%
observed molecular weight :
404.46
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
CLP 290 is a K+/Cl- Cotransporter 2 (KCC2) activator. Activates spinal inhibitory interneurons, restores physiological neuronal activity in the spinal cord and induces functional recovery in a mouse model of spinal cord injury. Also decreases blood vasopressin and glucose levels in mice with Streptozotocin (Cat. No. 1621) induced diabetes mellitus. Orally bioavailable prodrug of CLP 257 (Cat. No.5242).
top caption :
K+/Cl- cotransporter 2 (KCC2) activator; orally bioavailable prodrug of CLP 257 (Cat. No.5242)
extended description :
K+/Cl- cotransporter 2 (KCC2) activator; orally bioavailable prodrug of CLP 257 (Cat. No.5242)
chemical name text :
(Z)-5-Fluoro-2-((4-oxo-2-(tetrahydropyridazin-1(2H)-yl)thiazol-5(4H)-ylidene)methyl)phenyl pyrrolidine-1-carboxylate
formula :
C19H21FN4O3S
formula text :
C19H21FN4O3S
cas num :
1181083-81-7
USD :
265 USD
product details :
K+/Cl- cotransporter 2 (KCC2) activator; orally bioavailable prodrug of CLP 257 (Cat. No.5242)
storage :
Store at -20°C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK