LDC 000067 | Tocris Bioscience 6752 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

LDC 000067

catalog :

6752

quantity :

25 mg

price :

316 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

6752

SKU :

6752/25

product name :

LDC 000067

description :

Potent and selective CDK9 inhibitor

target :

Cyclin-dependent Kinase Inhibitors

category :

Small Molecules

unit size :

25 mg

purity :

98%

observed molecular weight :

370.43

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent and selective CDK9 inhibitor (IC50 = 44 nM at CDK9-cyclin T1). Inhibits other CDKs in the micromolar range (IC50 values are 2.4, 5.5, 9.2, 10 and 10 M for CDK2-cyclin A, CDK1-cyclin B1, CDK4-cyclin D1, CDK6-cyclin D3 and CDK7-cyclin H-MAT1, respectively). Inhibits P-TEFb-dependent in vitro transcription. Induces apoptosis in vitro and in vivo in combination with BI 894999.

catalog number base :

6752

product keywords :

LDC000067 LDC67 LDC067 potent selective CDK9 inhibitors inhibits Cyclin-dependent Kinase 6752,

extended description :

Potent and selective CDK9 inhibitor

chemical name text :

3-[[6-(2-Methoxyphenyl)-4-pyrimidinyl]amino]benzenemethanesulfonamide

formula :

C 18 H 18 N 4 O 3 S

formula text :

C18H18N4O3S

cas num :

1073485-20-7

2020 USD :

309

2021 USD :

316 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage