YNT 185 | Tocris Bioscience 6739 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

YNT 185

catalog :

6739

quantity :

10 mg

price :

279 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 6739 - YNT 185 C33H37N5O5S.2HCl CAS No. 1804978-82-2

product information

brand :

Tocris

master code :

6739

SKU :

6739/10

product name :

YNT 185

description :

Potent and selective OX2 agonist

target :

OX2 Receptor Agonists

category :

Small Molecules

unit size :

10 mg

purity :

98%

observed molecular weight :

688.66

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent and selective orexin OX2 receptor agonist (EC50 = 28 nM at human OX2 expressed in CHO cells). Displays approximately 100-fold selectivity for OX2 over OX1 (EC50 = 2.75 M at human OX1 expressed in CHO cells). Depolarizes OX2-expressing histaminergic neurons in mouse brain slices. Increases wake time in wild type mice. Suppresses cataplexy-like symptoms in OX knockout mice.

catalog number base :

6739

product keywords :

YNT185 orexin receptor 2 agonists agonism OX1 selective potent sleep wake cycle nacolepsy cataplexy OX2 Receptor 6739,

extended description :

Potent and selective OX2 agonist

chemical name text :

3 -[[[3-[[2-[[2-(Dimethylamino)benzoyl]amino]ethyl]amino]phenyl]amino]sulfonyl]-4 -methoxy-N,N-dimethyl-[1,1 -biphenyl]-3-carboxamide dihydrochloride

formula :

C 33 H 37 N 5 O 5 S.2HCl

formula text :

C33H37N5O5S.2HCl

cas num :

1804978-82-2

2020 USD :

279

2021 USD :

279 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage