YNT 185 | Tocris Bioscience 6739/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

YNT 185

catalog :

6739/10

quantity :

10 mg

price :

346 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 6739 - YNT 185 C33H37N5O5S.2HCl CAS No. 1804978-82-2

product information

brand :

Tocris

MasterCode :

6739

SKU :

6739/10

product name :

YNT 185

target :

OX2 Receptor Agonists

category :

Small Molecules

unit size :

10 mg

purity :

98%

observed molecular weight :

688.66

url print :

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details of functionality :

YNT 185 is a potent and selective orexin OX2 receptor agonist (EC50 = 28 nM at human OX2 expressed in CHO cells). Displays approximately 100-fold selectivity for OX2 over OX1 (EC50 = 2.75 M at human OX1 expressed in CHO cells). Depolarizes OX2-expressing histaminergic neurons in mouse brain slices. Increases wake time in wild type mice. Suppresses cataplexy-like symptoms in OX knockout mice.

extended description :

Potent and selective OX2 agonist

chemical name text :

3 -[[[3-[[2-[[2-(Dimethylamino)benzoyl]amino]ethyl]amino]phenyl]amino]sulfonyl]-4 -methoxy-N,N-dimethyl-[1,1 -biphenyl]-3-carboxamide dihydrochloride

formula :

C 33 H 37 N 5 O 5 S.2HCl

formula text :

C33H37N5O5S.2HCl

cas num :

1804978-82-2

USD :

346 USD

product details :

Potent and selective OX2 agonist

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage