A 77-01 | Tocris Bioscience 6712 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

A 77-01

catalog :

6712

quantity :

25 mg

price :

577 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

6712

SKU :

6712/25

product name :

A 77-01

description :

Potent inhibitor of TGF- RI

target :

TGF-beta Receptor Inhibitors

category :

Small Molecules

unit size :

25 mg

purity :

98%

observed molecular weight :

286.33

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent TGF- RI (ALK-5) inhibitor (IC50 = 34 nM). Inhibits TGF- transcriptional activation. Inhibits TGF- -induced proliferation of lung epithelial cells and SMAD phosphorylation. Inhibits TGF- -induced epithelial-to-mesenchymal transition (EMT). Also inhibitor of p38 MAPK. Likely active metabolite of A 83-01 (Cat. No. 2939).

catalog number base :

6712

product keywords :

A77-01 A7701 transforming growth factor receptor TGF B beta type I receptor kinase inhibitors inhibits potent p38 MAPK A 83-01 A83-01 TGF-beta Receptors p38 BMP and Other Activin Receptors 6712,

extended description :

Potent inhibitor of TGF- RI

chemical name text :

4-[3-(6-Methyl-2-pyridinyl)-1H-pyrazol-4-yl]quinoline

formula :

C 18 H 14 N 4

formula text :

C18H14N4

cas num :

607737-87-1

2020 USD :

577

2021 USD :

577 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage