chemical

DPNB-ABT 594

6706

5 mg

249 USD

6706

6706/5

DPNB-ABT 594

Caged ABT 594 (Cat. No. 6576); suitable for one- or two-photon photolysis

Nicotinic (a4b2) Receptor Agonists

Small Molecules

5 mg

98%

672.16

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Nitrobenzyl-caged ABT 594 (Cat. No. 6576), a selective 4 2 nAChR agonist. One-photon uncaging evokes large inward currents and Ca2+ transients on cell bodies and dendrites of medial habenular neurons in mouse brain slices. Two-photon uncaging induces fast nAChR-mediated currents. Photolyzed with high quantum yield of 0.20. Effective photolysis occurs using one- or two-photon excitation; one-photon uncaging requires illumination at 410 nm for 1.5-3 ms; two-photon uncaging requires illumination with appropriate two photon pulse laser at 710 nm for ~2 ms.

6706

caged agonists ABT 594 photoactivatable nicotine nicotinics cholinergics activators acetylcholine receptors nAChRs a4b2 Nicotinic (a4b2) Receptors Caged Nicotinic Compounds 6706,

Caged ABT 594 (Cat. No. 6576); suitable for one- or two-photon photolysis

5-(((2R)-1-(1-(4,5-Bis(2-(2-(2-methoxyethoxy)ethoxy)ethoxy)-2-nitrophenyl)ethyl)azetidin-2-yl)methoxy)-2-chloropyridine

C 31 H 46 ClN 3 O 11

C31H46ClN3O11

249

249 USD

Store at -20°C