product summary
Loading...
company name :
Tocris Bioscience
product type :
chemical
product name :
BGP 15
catalog :
6703
quantity :
25 mg
price :
449 USD
more info or order :
Tocris Bioscience product webpage
product information
brand :
Tocris
master code :
6703
SKU :
6703/25
product name :
BGP 15
description :
PARP inhibitor; cytoprotectant
target :
Poly(ADP-ribose) Polymerase Inhibitors
category :
Small Molecules
unit size :
25 mg
purity :
98%
observed molecular weight :
351.27
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
PARP inhibitor (IC50 = 120 M). Displays cytoprotective effects in various disease models: decreases ROS levels, lipid peroxidation and single-strand DNA breaks in isolated reperfused rat hearts; improves mitochondrial function and protects against neuronal cell death in a mouse model of familial dysautonomia. Also activates HSP70 in rodent skeletal muscle, increasing oxidative capacity and improving insulin sensitivity.
catalog number base :
6703
product keywords :
BGP15 cytoprotectant chemoprotectant PARP inhibitors inhibits Hsp70 protein 1 Hsp72 activators activates Poly(ADP-ribose) Polymerase Hsp70 6703,
extended description :
PARP inhibitor; cytoprotectant
chemical name text :
N-[2-Hydroxy-3-(1-piperidinyl)propoxy]-3-pyridinecarboximidamide dihydrochloride
formula :
C 14 H 22 N 4 O 2 .2HCl
formula text :
C14H22N4O2.2HCl
cas num :
66611-37-8
2020 USD :
449
2021 USD :
449 USD
storage :
Store at -20°C
more info or order :
Tocris Bioscience product webpage
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK