product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
BGP 15
catalog :
6703/5
quantity :
5 mg (also 25 mg)
price :
146 USD
more info or order :
image
image 1 :
Tocris Bioscience 6703/5 image 1
Cat.No. 6703 - BGP 15 C14H22N4O2.2HCl CAS No. 66611-37-8
product information
brand :
Tocris, a Bio-Techne brand
catalog number base :
6703
SKU :
6703/5
product name :
BGP 15
description :
PARP inhibitor; cytoprotectant
target :
Poly(ADP-ribose) Polymerase Inhibitors
unit size :
5 mg (also 25 mg)
category :
Small Molecules
purity :
98%
storage :
Store at -20°C
observed molecular weight :
351.27
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
BGP 15 is a PARP inhibitor (IC50 = 120 M). Displays cytoprotective effects in various disease models: decreases ROS levels, lipid peroxidation and single-strand DNA breaks in isolated reperfused rat hearts; improves mitochondrial function and protects against neuronal cell death in a mouse model of familial dysautonomia. BGP 15 also activates HSP70 in rodent skeletal muscle, increasing oxidative capacity and improving insulin sensitivity.
product keywords :
BGP15 cytoprotectant chemoprotectant PARP inhibitors inhibits Hsp70 protein 1 Hsp72 activators activates Poly(ADP-ribose) Polymerase Hsp70 6703,
extended description :
PARP inhibitor; cytoprotectant
chemical name text :
N-[2-Hydroxy-3-(1-piperidinyl)propoxy]-3-pyridinecarboximidamide dihydrochloride
formula :
C14H22N4O2.2HCl
formula text :
C14H22N4O2.2HCl
cas num :
66611-37-8
USD :
144
USD 2025 :
146 USD
product details :
PARP inhibitor; cytoprotectant
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK