1A-116 | Tocris Bioscience 6701 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

1A-116

catalog :

6701

quantity :

10 mg (also 50 mg)

price :

199 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

6701

SKU :

6701/10

product name :

1A-116

description :

Rac1 inhibitor; blocks Rac1-P-Rex1 interaction

target :

Rho GTPase Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

307.31

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Rac1 inhibitor. Reduces intracellular Rac1-GTP levels and blocks Rac1-P-Rex1 interaction in vitro . Exhibits no effect on GTPase activity of closely related Cdc42. Displays antiproliferative, anti-invasive and pro-apoptotic activity in several cancer cell lines. Exhibits antimetastatic activity in vivo . Also restores antiproliferative effects of Tamoxifen (Cat. No. 6342) in resistant breast cancer cell.

catalog number base :

6701

product keywords :

rac1 gtpase inhibitors inhibits tamoxifen resistance breast cancer Rho 6701,

extended description :

Rac1 inhibitor; blocks Rac1-P-Rex1 interaction

chemical name text :

N-(3,5-Dimethylphenyl)-N -[2-(trifluoromethyl)phenyl]guanidine

formula :

C 16 H 16 F 3 N 3

formula text :

C16H16F3N3

cas num :

1430208-73-3

2020 USD :

199

2021 USD :

199 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage