[D-Ala2]-GIP (human) | Tocris Bioscience 6699/1 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

[D-Ala2]-GIP (human)

catalog :

6699/1

quantity :

1 mg

price :

472 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Zhang C, Vincelette L, Reimann F, Liberles S. A brainstem circuit for nausea suppression. Cell Rep. 2022;39:110953 pubmed publisher
Killion E, Chen M, Falsey J, Sivits G, Hager T, Atangan L, et al. Chronic glucose-dependent insulinotropic polypeptide receptor (GIPR) agonism desensitizes adipocyte GIPR activity mimicking functional GIPR antagonism. Nat Commun. 2020;11:4981 pubmed publisher

product information

brand :

Tocris

MasterCode :

6699

SKU :

6699/1

product name :

[D-Ala2]-GIP (human)

target :

GIP Receptor Agonists

category :

Peptides

unit size :

1 mg

purity :

95%

observed molecular weight :

4983.58

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=peptides

details of functionality :

[D-Ala2]-GIP (human) is a highly potent GIP receptor agonist (EC50 = 630 119 pM). Displays equivalent cAMP stimulating properties and improved resistance to enzymatic degradation compared to native GIP (Cat. No. 2084) in cells expressing wild type GIP receptor. Improves glucose tolerance, insulin release and cognitive function in various animal models of obesity and diabetes. Displays neuroprotective effects in an MPTP model of PD.

extended description :

Highly potent GIP agonist

formula :

C 226 H 338 N 60 O 66 S

formula text :

C226H338N60O66S

cas num :

444073-04-5

USD :

472 USD

product details :

Highly potent GIP agonist

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage