CHIR 98014 | Tocris Bioscience 6695 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

CHIR 98014

catalog :

6695

quantity :

25 mg

price :

490 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

6695

SKU :

6695/25

product name :

CHIR 98014

description :

Highly potent and selective GSK-3 inhibitor

target :

Glycogen Synthase Kinase Inhibitors

category :

Small Molecules

unit size :

25 mg

purity :

98%

observed molecular weight :

486.31

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Highly potent and selective GSK-3 inhibitor (IC50 values are 0.58 and 0.65 nM for the and isoforms, respectively). Exhibits 500-fold selectivity for GSK-3 over a range of other kinases. Improves insulin sensitivity of muscle strips from diabetic rats in vitro and decreases insulin and glucose levels in the oral glucose tolerance test in vivo . Activates Wnt signaling in human adipose stem cells (hASC) and promotes the production of definitive endoderm. Has been used in protocols to derive epicardial cells from hPSCs.

catalog number base :

6695

product keywords :

CHIR98014 glycogen synthase kinase 3 alpha alfa beta inhibitors inhibits highly potent selective GSK Wnt signaling activates activators reprogramming epicardial cells Glycogen Synthase Kinase 3 Stem Cell Reprogramming 6695,

extended description :

Highly potent and selective GSK-3 inhibitor

chemical name text :

N6-[2-[[4-(2,4-Dichlorophenyl)-5-(1H-imidazol-1-yl)-2-pyrimidinyl]amino]ethyl]-3-nitro-2,6-pyridinediamine

formula :

C 20 H 17 Cl 2 N 9 O 2

formula text :

C20H17Cl2N9O2

cas num :

252935-94-7

2020 USD :

475

2021 USD :

490 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage