WM 1119 | Tocris Bioscience 6692 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

WM 1119

catalog :

6692

quantity :

10 mg (also 50 mg)

price :

212 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

6692

SKU :

6692/10

product name :

WM 1119

description :

High affinity KAT6A (MOZ) competitive inhibitor

target :

Histone Acetyltransferase Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

389.38

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

High affinity and competitive lysine acetyltransferase 6A (KAT6A/MOZ) inhibitor (Kd = 2 nM). Displays 250-fold affinity for KAT6A compared to KAT5 and KAT7. Induces cell-cycle exit and cellular senescence, and inhibits growth of B-cell lymphoma cells in vitro (IC50 = 0.25 M). Reduces H3K9ac in tumor cells, and decreases tumor burden and spleen weight in a mouse lymphoma model.

catalog number base :

6692

product keywords :

WM1119 KAT6A KAT 6A MOZ inhibitors inhibits competitive high affinity lysine histone acetyltransferase HAT Histone Acetyltransferases 6692,

extended description :

High affinity KAT6A (MOZ) competitive inhibitor

chemical name text :

2-Fluoro-N -(3-fluoro-5-(pyridin-2-yl)benzoyl)benzenesulfonohydrazide

formula :

C 18 H 13 F 2 N 3 O 3 S

formula text :

C18H13F2N3O3S

cas num :

2055397-28-7

2020 USD :

203

2021 USD :

212 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage