Thalidomide, propargyl | Tocris Bioscience 6685/50 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Thalidomide, propargyl

catalog :

6685/50

quantity :

50 mg

price :

530 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 6685 - Thalidomide, propargyl C16H12N2O5 CAS No. 2098487-39-7

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

6685

SKU :

6685/50

product name :

Thalidomide, propargyl

description :

Alkyne-functionalized Thalidomide; 'click' cereblon ligand for PROTACs

target :

Degrader Building Blocks

unit size :

50 mg

category :

Small Molecules

purity :

95%

storage :

Store at -20°C

observed molecular weight :

312.28

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Thalidomide, propargyl is a click-activated Thalidomide (Cat.No. 0652); can be used as a precursor to a PROTAC that hijacks cereblon as the E3 ubiquitin ligase component. Supplied with an alkyne functional handle at a position known not to significantly affect binding to cereblon, for ready click conjugation to a linker/target protein ligand. . Please contact us for SD files of our available Degrader Building Blocks. . PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license. . Require a different derivative? Get in touch .

product keywords :

PROTACs click-activated thalidomide E3 ligase ligands cereblon PROTAC Toolbox targeted protein degradation development Functionalized E3 Ligase Ligands 6685,

extended description :

Alkyne-functionalized Thalidomide; 'click' cereblon ligand for PROTACs

chemical name text :

2-(2,6-Dioxo-3-piperidinyl)-4-(2-propyn-1-yloxy)-1H-isoindole-1,3(2H)-dione

formula :

C16H12N2O5

formula text :

C16H12N2O5

cas num :

2098487-39-7

USD :

523

USD 2025 :

530 USD

product details :

Alkyne-functionalized Thalidomide; 'click' cereblon ligand for PROTACs

more info or order :

Tocris Bioscience product webpage