product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
Silodosin
catalog :
6663/10
quantity :
10 mg (also 50 mg)
price :
116 USD
more info or order :
citations: 1
Reference
Chou W, Chen W, Shen C. A common variant in 11q23.3 associated with hyperlipidemia is mediated by the binding and regulation of GATA4. NPJ Genom Med. 2022;7:4 pubmed publisher
image
image 1 :
Tocris Bioscience 6663/10 image 1
Cat.No. 6663 - Silodosin C25H32F3N3O4 CAS No. 160970-54-7
product information
brand :
Tocris, a Bio-Techne brand
catalog number base :
6663
SKU :
6663/10
product name :
Silodosin
description :
Selective 1A antagonist
target :
Adrenergic alpha-1 Receptor Antagonists
unit size :
10 mg (also 50 mg)
category :
Small Molecules
purity :
98%
storage :
Store at -20°C
observed molecular weight :
495.53
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Silodosin is a selective 1A adrenoceptor antagonist (Ki = 0.036 nM). Displays 55 fold selectivity for 1A over 1B and 1D. Inhibits norepinephrine-induced [Ca2+]I increase in 1A expressing CHO cells (IC50 = 0.32 nM). Inhibits norepinephrine-induced contraction of isolated human prostate tissue.
product keywords :
alpha 1a adrenoceptor adrenergic receptor antagonists antagonism KMD-3213 Adrenergic Alpha-1 Receptors 6663,
extended description :
Selective 1A antagonist
chemical name text :
2,3-Dihydro-1-(3-hydroxypropyl)-5-[(2R)-2-[[2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethyl]amino]propyl]-1H-indole-7-carboxamide
formula :
C25H32F3N3O4
formula text :
C25H32F3N3O4
cas num :
160970-54-7
USD :
128
USD 2025 :
116 USD
product details :
Selective 1A antagonist
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK