PA 8 | Tocris Bioscience 6657 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

PA 8

catalog :

6657

quantity :

10 mg (also 50 mg)

price :

167 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

6657

SKU :

6657/10

product name :

PA 8

description :

PAC1 receptor antagonist

target :

PACAP Receptor Antagonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

342.35

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

PAC1 receptor antagonist. Inhibits PACAP-induced CREB phosphorylation in PAC1, but not VPAC1 or VPAC2, expressing cells. Also inhibits PACAP-induced increases in cAMP levels in vitro (IC50 = 2 nM) and PACAP-induced aversive responses and mechanical allodynia following intrathecal injection in vivo .

catalog number base :

6657

product keywords :

PA8 Pituitary adenylate cyclase-activating polypeptide PACAP receptors antagonists antagonism PAC1 analgesics analgesia PACAP Receptors 6657,

extended description :

PAC1 receptor antagonist

chemical name text :

2-Amino-5,8-dihydro-5-[3-methoxy-4-(2-propen-1-yloxy)phenyl]pyrido[2,3-d]pyrimidine-4,7(3H,6H)-dione

formula :

C 17 H 18 N 4 O 4

formula text :

C17H18N4O4

cas num :

878437-15-1

2020 USD :

160

2021 USD :

167 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage