QWF | Tocris Bioscience 6642/5 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

QWF

catalog :

6642/5

quantity :

5 mg

price :

197 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Song M, Shim W. Lithocholic Acid Activates Mas-Related G Protein-Coupled Receptors, Contributing to Itch in Mice. Biomol Ther (Seoul). 2021;: pubmed publisher

product information

brand :

Tocris

master code :

6642

SKU :

6642/5

rank :

0.06

product name :

QWF

description :

MRGPRX2 antagonist; also NK1 receptor antagonist

target :

Mas-Related G Protein Coupled Receptor Antagonists

category :

Peptides

sizes available :

5 mg

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=peptides

details of functionality :

QWF is a tripeptide substance P (SP) antagonist (IC50 = 90 M). Also inhibits binding of SP to Mas-related GPCR (MRGPR) X2. Inhibits SP-induced IgE-independent degranulation of mast cells in vitro . Inhibits compound 48/80-induced MRGPRX2 activation and scratching in mice in vivo . . For more information about how QWF may be used, see our protocol: 3D Culture of Lung Alveolar Cells

extended description :

MRGPRX2 antagonist; also NK1 receptor antagonist

formula :

C 38 H 43 N 5 O 8

formula text :

C38H43N5O8

cas num :

126088-82-2

USD :

197 USD

product details :

MRGPRX2 antagonist; also NK1 receptor antagonist

storage :

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

more info or order :

Tocris Bioscience product webpage