GSK 626616 | Tocris Bioscience 6638 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

GSK 626616

catalog :

6638

quantity :

10 mg (also 50 mg)

price :

205 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

6638

SKU :

6638/10

product name :

GSK 626616

description :

Potent and selective DYRK inhibitor; orally bioavailable.

target :

DYRK Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

401.27

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent and selective DYRK inhibitor (IC50 = 0.7 nM for DYRK3, similar potency for DYRK1 and 2). Exhibits ~20-fold selectivity over casein kinase 2 and negligible activity against a panel of 451 kinases screened. Enhances number of CFU-E stimulated by Epo from human marrow. Increases hemoglobin levels in anemic mice. Orally bioavailable.

catalog number base :

6638

product keywords :

GSK626616 potent dyrk1 dyrk2 dyrk3 dual specificity tyrosine phosphorylation regulated kinases inhibitors inhibits selective DYRK 6638,

extended description :

Potent and selective DYRK inhibitor; orally bioavailable.

chemical name text :

(5Z)-2-[(2,6-Dichlorophenyl)amino]-5-(6-quinoxalinylmethylene)-4(5H)-thiazolone

formula :

C 18 H 10 Cl 2 N 4 OS

formula text :

C18H10Cl2N4OS

cas num :

1025821-33-3

2020 USD :

197

2021 USD :

205 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage