product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
ERGi-USU
catalog :
6632
quantity :
50 mg
price :
50 USD
more info or order :
Tocris Bioscience product webpage
product information
brand :
Tocris
master code :
6632
SKU :
6632/50
product name :
ERGi-USU
description :
Rio2 kinase (RIOK2) inhibitor; inhibits ERG protein
target :
Other Kinase Inhibitors
category :
Small Molecules
unit size :
50 mg
purity :
99%
observed molecular weight :
255.3
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
High affinity Rio Kinase 2 (RIOK2) inhibitor (Kd = 200 nM). Exhibits 6-fold selectivity for RIOK2 over a panel of 456 kinases. Inhibits ERG protein and potently inhibits growth of ERG-positive VCaP prostate cancer cells in vitro (IC50 = 169 nM) but not ERG-negative cell lines. Also inhibits growth of VCaP xenografts in mice.
catalog number base :
6632
product keywords :
Rio2 kinase RIOK2 atypical protein kinase aPK ribosome biogenesis inhibitors inhibits high affinity ERG protein prostate cancer Other Kinases 6632,
extended description :
Rio2 kinase (RIOK2) inhibitor; inhibits ERG protein
chemical name text :
1-[2-(2-Thiazolyl)diazenyl]-2-naphthalenol
formula :
C 13 H 9 N 3 O S
formula text :
C13H9N3OS
cas num :
1147-56-4
2020 USD :
49
2021 USD :
50 USD
storage :
Store at +4°C
more info or order :
Tocris Bioscience product webpage
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK