AP C5 | Tocris Bioscience 6626/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

AP C5

catalog :

6626/10

quantity :

10 mg (also 50 mg)

price :

137 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 6626 - AP C5 C16H13N5 CAS No. 2234272-10-5

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

6626

SKU :

6626/10

product name :

AP C5

description :

Potent and selective PKG2 inhibitor

target :

Protein Kinase G Inhibitors

unit size :

10 mg (also 50 mg)

category :

Small Molecules

purity :

98%

storage :

Store at -20°C

observed molecular weight :

275.31

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

AP C5 is a potent and selective protein kinase G type II (PKG2) inhibitor (pIC50 = 7.2). Displays 20-fold selectivity for PKG2 over PKG1 and PKA (pIC50 values are 4.6 and 4.8 for PKG1 and PKA, respectively). Blocks 8-pCPT-cGMP-dependent VASP phosphorylation in intestinal organoids. Also attenuates toxin-stimulated anion secretory responses in mouse intestinal tissue.

product keywords :

APC5 protein kinase g type 2 II inhibitors inhibits guanosine 3,5-cyclic monophosphate dependent protein kinase Protein Kinase G 6626,

extended description :

Potent and selective PKG2 inhibitor

chemical name text :

4-[4-(1H-Imidazol-1-yl)phenyl]-N-2-propyn-1-yl-2-pyrimidinamine

formula :

C16H13N5

formula text :

C16H13N5

cas num :

2234272-10-5

USD :

152

USD 2025 :

137 USD

product details :

Potent and selective PKG2 inhibitor

more info or order :

Tocris Bioscience product webpage