product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
MB 05032
catalog :
6618
quantity :
10 mg (also 50 mg)
price :
212 USD
more info or order :
product information
brand :
Tocris
master code :
6618
SKU :
6618/10
product name :
MB 05032
description :
Potent FBPase inhibitor; promotes HSC expansion
target :
Other Transferase Inhibitors
category :
Small Molecules
unit size :
10 mg (also 50 mg)
purity :
98%
observed molecular weight :
302.29
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Potent FBPase inhibitor (EC50 values are 1.6, 29 and 61 nM for human liver FBPase, human muscle FBPase and rat liver FBPase). Promotes hematopoietic stem cell and progenitor cell expansion. Increases engraftment in primary NSG mice recipients. Also enhances myeloid and lymphoid chimerism in secondary NSG mouse recipients. Promotes glycolysis, glucose uptake and lactate production in umbilical cord blood CD34+ cells.
catalog number base :
6618
product keywords :
MB05032 potent FBPase inhibitors fructose 1 6 bisphosphatase diabetes HSC expansion gluconeogenesis hematopoietic stem cell haematopoietic Other Transferases Stem Cell Proliferation 6618,
extended description :
Potent FBPase inhibitor; promotes HSC expansion
chemical name text :
P-[5-[2-Amino-5-(2-methylpropyl)-4-thiazolyl]-2-furanyl]phosphonic acid
formula :
C 11 H 15 N 2 O 4 PS
formula text :
C11H15N2O4PS
cas num :
261365-11-1
2020 USD :
205
2021 USD :
212 USD
storage :
Store at -20°C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK