Yhhu 3792 | Tocris Bioscience 6599/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Yhhu 3792

catalog :

6599/10

quantity :

10 mg

price :

435 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Morales R, Rabahi S, Diaz O, Salloum Y, Kern B, Westling M, et al. Interleukin-10 regulates goblet cell numbers through Notch signaling in the developing zebrafish intestine. Mucosal Immunol. 2022;15:940-951 pubmed publisher

image

image 1 :

Cat.No. 6599 - Yhhu 3792 C24H24N4O2.HCl

product information

brand :

Tocris

MasterCode :

6599

SKU :

6599/10

product name :

Yhhu 3792

target :

Compounds for NSC Proliferation and Renewal

category :

Small Molecules

unit size :

10 mg

purity :

98%

observed molecular weight :

436.93

url print :

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details of functionality :

Yhhu 3792 is a notch signaling pathway activator; enhances the self-renewal capability of neural stem cells (NSCs) via Notch signaling pathway activation in vitro and in vivo . Promotes the expression of Notch target genes, Hes3 and Hes5 . Expands the NSCs pool and promotes endogenous neurogenesis in the hippocampal dentate gyrus (DG) after chronic administration in mice. Increases the spatial and episodic memory in mice.

extended description :

Notch signaling pathway activator; enhances the self-renewal capability of NSCs; active in vivo

chemical name text :

5-(3-Methoxyphenoxy)-N2-[4-(1-methylethyl)phenyl]-2,4-quinazolinediamine hydrochloride

formula :

C 24 H 24 N 4 O 2 .HCl

formula text :

C24H24N4O2.HCl

cas num :

2624336-93-0

USD :

435 USD

product details :

Notch signaling pathway activator; enhances the self-renewal capability of NSCs; active in vivo

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage