TAK 242 | Tocris Bioscience 6587 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

TAK 242

catalog :

6587

quantity :

5 mg

price :

192 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

6587

SKU :

6587/5

product name :

TAK 242

description :

TLR4 signaling inhibitor

target :

Toll-like Receptor Inhibitors

category :

Small Molecules

unit size :

5 mg

purity :

98%

observed molecular weight :

361.82

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Toll-like receptor 4 (TLR4) signaling inhibitor. Binds to intracellular domain of TLR4. Inhibits LPS-induced cytokine production in vitro (IC50 values are 1.3, 1.3 and 3.2 nM for IL-6, TNF and NO production). Reduces lesion volume in a mouse model of cerebral cavernous malformations (CCMs). Also attenuates increased cytokine levels in a mouse sepsis model, when given in combination with ceftazidime. Cell permeable.

catalog number base :

6587

product keywords :

TAK242 toll like receptor TLR4 signaling inhibitor inhibits sepsis cell permeable Toll-like Receptors 6587,

extended description :

TLR4 signaling inhibitor

chemical name text :

(R)-Ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-enecarboxylate

formula :

C 15 H 17 ClFNO 4 S

formula text :

C15H17ClFNO4S

cas num :

243984-11-4

2020 USD :

182

2021 USD :

192 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage