Targapremir 210 | Tocris Bioscience 6586 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Targapremir 210

catalog :

6586

quantity :

5 mg

price :

265 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 6586 - Targapremir 210 C32H36N10O2 CAS No. 1049722-30-6

product information

brand :

Tocris

master code :

6586

SKU :

6586/5

product name :

Targapremir 210

description :

Inhibits formation of miR-210

target :

DNA, RNA and Protein Synthesis Inhibitors

category :

Small Molecules

unit size :

5 mg

purity :

98%

observed molecular weight :

592.71

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Inhibits formation of miR-210 by binding to pre-miR-210 Dicer binding site (Kd ~ 200 nM). Decreases levels of miR-210 and HIF-1 mRNA, and induces apoptosis in MDA-MB-231 cells cultured under hypoxic conditions. Reduces tumor expression of HIF-1 mRNA and miR-210, and tumor growth in a triple negative breast cancer mouse model.

catalog number base :

6586

product keywords :

micro RNA miRNA inhibitors inhibits miR-210 triple negative breast cancer hypoxia HIF1a alpha alfa DNA, RNA and Protein Synthesis 6586,

extended description :

Inhibits formation of miR-210

chemical name text :

N-(3-Azidopropyl)-4-[3-[6-(4-methyl-1-piperazinyl)[2,6 -bi-1H-benzimidazol]-2 -yl]phenoxy]butanamide

formula :

C 32 H 36 N 10 O 2

formula text :

C32H36N10O2

cas num :

1049722-30-6

2020 USD :

265

2021 USD :

265 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage