Targapremir 210 | Tocris Bioscience 6586/5 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Targapremir 210

catalog :

6586/5

quantity :

5 mg

price :

297 USD

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

6586

SKU :

6586/5

product name :

Targapremir 210

description :

Inhibits formation of miR-210

target :

DNA, RNA and Protein Synthesis Inhibitors

unit size :

5 mg

category :

Small Molecules

purity :

98%

storage :

Store at -20°C

observed molecular weight :

592.71

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Targapremir 210 inhibits formation of mature miR-210 (IC50 = 200 nM) by binding to Dicer binding site of the miR-210 hairpin precursor (Kd = 200 nM) and inhibits Dicer processing of the miRNA. Decreases levels of miR-210 and HIF-1 mRNA, and induces apoptosis in MDA-MB-231 cells cultured under hypoxic conditions. Reduces tumor expression of HIF-1 mRNA and miR-210, and tumor growth in a triple negative breast cancer mouse model.

product keywords :

micro RNA miRNA inhibitors inhibits miR-210 triple negative breast cancer hypoxia HIF1a alpha alfa DNA, RNA and Protein Synthesis 6586,

extended description :

Inhibits formation of miR-210

chemical name text :

N-(3-Azidopropyl)-4-[3-[6-(4-methyl-1-piperazinyl)[2,6 -bi-1H-benzimidazol]-2 -yl]phenoxy]butanamide

formula :

C32H36N10O2

formula text :

C32H36N10O2

cas num :

1049722-30-6

USD :

329

USD 2025 :

297 USD

product details :

Inhibits formation of miR-210