PKUMDL WQ 2101 | Tocris Bioscience 6580 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

PKUMDL WQ 2101

catalog :

6580

quantity :

25 mg

price :

275 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

6580

SKU :

6580/25

product name :

PKUMDL WQ 2101

description :

Negative allosteric modulator of 3-phosphoglycerate dehydrogenase (PHGDH)

target :

Dehydrogenase Inhibitors

category :

Small Molecules

unit size :

25 mg

purity :

98%

observed molecular weight :

317.25

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Negative allosteric modulator of phosphoglycerate dehydrogenase (PHGDH) (IC50 = 34.8 M). Exhibits antitumor activity in vitro in breast cancer cells lines overexpressing PHGDH (EC50 values are 7.7 and 10.8 M in MDA-MB-468 and HCC-70 cells, respectively). Inhibits growth of MDA-MB-468 xenografts in mice.

catalog number base :

6580

product keywords :

PKUMDLWQ2101 Phosphoglycerate dehydrogenase PHGDH allosteric inhibitor serine biosynthesis negative modulator NAM Other Dehydrogenases 6580,

extended description :

Negative allosteric modulator of 3-phosphoglycerate dehydrogenase (PHGDH)

chemical name text :

2,4-Dihydroxy-N -(2-hydroxy-5-nitrobenzylidene)benzohydrazide

formula :

C 14 H 11 N 3 O 6

formula text :

C14H11N3O6

cas num :

304481-72-9

2020 USD :

269

2021 USD :

275 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage