BAY 826 | Tocris Bioscience 6579/5 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

BAY 826

catalog :

6579/5

quantity :

5 mg (also 25 mg)

price :

136 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Rada M, Kapelanski Lamoureux A, Tsamchoe M, Petrillo S, Lazaris A, Metrakos P. Angiopoietin-1 Upregulates Cancer Cell Motility in Colorectal Cancer Liver Metastases through Actin-Related Protein 2/3. Cancers (Basel). 2022;14: pubmed publisher

image

image 1 :

Cat.No. 6579 - BAY 826 C26H19F5N6OS CAS No. 1448316-08-2

product information

brand :

Tocris

catalog number base :

6579

SKU :

6579/5

product name :

BAY 826

units size :

5 mg (also 25 mg)

description :

Potent Tie2 inhibitor

target :

Additional RTK Inhibitors

category :

Small Molecules

purity :

98%

observed molecular weight :

558.53

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

BAY 826 is a potent Tie 2 inhibitor (IC50 = 1.3 nM for autophosphorylation of Tie2 in HUVECs), which is selective for Tie2 over other angiogenic receptor tyrosine kinases, including VEGFR, FGFR and PDGFR. BAY 826 displays in vivo efficacy in some murine glioma models. . Tie2 is also known as angiopoietin-1 receptor and TEK tyrosine kinase.

top caption :

Potent Tie2 inhibitor

extended description :

Potent Tie2 inhibitor

chemical name text :

[3-Cyano-5-[[[2,4-dimethyl-5-[6-(3-pyridinyl)-1H-imidazo[1,2-b]pyrazol-1-yl]phenyl]amino]carbonyl]phenyl]pentafluorosulfur

formula :

C26H19F5N6OS

formula text :

C26H19F5N6OS

cas num :

1448316-08-2

USD :

136 USD

product details :

Potent Tie2 inhibitor

storage :

Store at -20Â°C

more info or order :

Tocris Bioscience product webpage