Biotin-NAD+ | Tocris Bioscience 6573/131U product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Biotin-NAD+

catalog :

6573/131U

quantity :

131 ug

price :

423 USD

more info or order :

Tocris Bioscience product webpage

citations: 3

Reference
Cardamone M, Gao Y, Kwan J, Hayashi V, Sheeran M, Xu J, et al. Neuralized-like protein 4 (NEURL4) mediates ADP-ribosylation of mitochondrial proteins. J Cell Biol. 2022;221: pubmed publisher
Yang C, Jividen K, Spencer A, Dworak N, Ni L, Oostdyk L, et al. Ubiquitin Modification by the E3 Ligase/ADP-Ribosyltransferase Dtx3L/Parp9. Mol Cell. 2017;66:503-516.e5 pubmed publisher
Yang F, Nickols N, Li B, Marinov G, Said J, Dervan P. Antitumor activity of a pyrrole-imidazole polyamide. Proc Natl Acad Sci U S A. 2013;110:1863-8 pubmed publisher

product information

brand :

Tocris

MasterCode :

6573

SKU :

6573/131U

product name :

Biotin-NAD+

target :

Buffers, Chelators and Reagents

category :

Small Molecules

unit size :

131 ug

observed molecular weight :

1045.95

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Biotin-NAD+ is a provides a convenient non-isotopic alternative to radiolabeled NAD+ for determination of IC50 values for candidate PARP inhibitors and studies requiring this substrate. Biotinylated-NAD+ allows an indirect measure of PARP activity when biotin incorporation is detected using a conjugated-streptavidin detection system. Acts as a substrate for ADP-ribosylation. Can be used to label and purify biotinyl-ADP ribosylated proteins. . This product is a replacement for R&D Systems product 4670-500-01 . . 131 g is supplied as 500 l of a 0.25 mM solution in water.

extended description :

Biotinylated-NAD+; substrate for ADP-ribosylation

chemical name text :

-Nicotinamide-N6-[2-[[6-[biotinyl]amino]hexyl]amino]-2-oxoethyl]adenine dinucleotide

formula :

C 39 H 57 N 11 O 17 P 2 S

formula text :

C39H57N11O17P2S

cas num :

146385-37-7

USD :

423 USD

product details :

Biotinylated-NAD+; substrate for ADP-ribosylation

storage :

Store at -80°C

more info or order :

Tocris Bioscience product webpage