Dooku 1 | Tocris Bioscience 6568/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Dooku 1

catalog :

6568/10

quantity :

10 mg (also 50 mg)

price :

164 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

6568

SKU :

6568/10

rank :

0.06

product name :

Dooku 1

description :

Reversibly blocks Yoda1 activity; does not affect constitutive Piezo1 activity

target :

Other Piezo Channel Compounds

category :

Small Molecules

sizes available :

10 mg (also 50 mg)

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Dooku 1 reversibly blocks Yoda1 (Cat. No. 5586) activity (IC50 = ~1.5 M). Exhibits no effect on constitutive Piezo1 channel activity, but antagonizes Yoda1-induced Piezo1 activation in endothelial cells, and inhibits Yoda1-induced Ca2+-entry in vitro . Also blocks Yoda1-induced relaxation of aorta ex vivo .

extended description :

Reversibly blocks Yoda1 activity; does not affect constitutive Piezo1 activity

chemical name text :

2-[(2,6-Dichlorobenzyl)thio)-5-(1H-pyrrol-2-yl)-1,3,4-oxadiazole

formula :

C 13 H 9 Cl 2 N 3 OS

formula text :

C13H9Cl2N3OS

cas num :

2253744-54-4

USD :

164 USD

product details :

Reversibly blocks Yoda1 activity; does not affect constitutive Piezo1 activity

storage :

Store the unopened product at 2 - 8 °C. Do not use past expiration date.

more info or order :

Tocris Bioscience product webpage